Psychiatric morbidity in patients with lung cancer.

journal.publications.chestnet.org of lesions associated with TBI is compounded by the Marshall clas sifi cation of head injury based on CT scanning. 2 These conditions cause coma when they affect brain perfusion and cortical or brain stem activity. DAI is only one possible physiopathologic mechanism causing coma after TBI and typically occurs during high-speed impact trauma causing rotational acceleration. This causes axonal damage, as the axons are torn or stretched, thus, impairing axoplasmic transport and, ultimately, the electrical neural network. 3 It should be noted that, when dealing with DAI, CT scanning can offer some clues to diagnosis, 4 but it is often inaccurate in identifying injuries. MRI can clearly detect DAI deep lesions. Moreover, MRI is potentially useful as a clue to prognosis because it assesses the severity of DAI, which is classifi ed as mild (as only corticosubcortical lesions are apparent), moderate (as corpus callosum is involved), or severe (as brain stem is involved). 5